interface graph thumbnail
legend  pdf

structure nameBASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE
(Recombinase CRE)
referenceBaldwin et al.
sourceEnterobacteria phage P1
experimentX-ray (resolution=2.65, R-factor=0.212)
structural superfamilyDNA breaking-rejoining enzymes;lambda integrase-like, N-terminal domain;
sequence familyPhage integrase family;
multimeric complexes1kbu_AB 1ma7_AB 1nzb_AB 1ouq_AB 1ouq_EF 1pvp_AB 1pvq_AB 1pvr_AB 1q3v_AB 1q3v_EF 1xo0_AB 2hof_AB 2hoi_GH 3c28_AB 3c29_AB 3mgv_AB 3mgv_CD 4crx_AB 5crx_AB 7rhx_AB 7rhz_AB
reference complex7rhx_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureMSTQRKSSR

Estimated binding specificities ?

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# IC=3.834 IC/col=0.349 n_of_columns=11 specificity:   
A |  11  24  24  24  24   8  24  24   1  72   0
C |   8  24  24  24  24  11  24  24   0   8   0
G |   8  24  24  24  24   8  24  24   8   8   0
T |  69  24  24  24  24  69  24  24  87   8  96
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updated Mon Dec 18 05:50:32 2023