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legend  pdf

structure nameBASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7
(Recombinase cre)
referenceBaldwin et al.
sourceEscherichia phage P1
experimentX-ray (resolution=2.75, R-factor=0.224)
structural superfamilyDNA breaking-rejoining enzymes;lambda integrase-like, N-terminal domain;
sequence familyPhage integrase family;
multimeric complexes1kbu_AB 1ma7_AB 1nzb_AB 1ouq_AB 1ouq_EF 1pvp_AB 1pvq_AB 1pvr_AB 1q3v_AB 1q3v_EF 1xo0_AB 2hof_AB 2hoi_GH 3c28_AB 3c29_AB 3mgv_AB 3mgv_CD 4crx_AB 5crx_AB 7rhx_AB 7rhz_AB
reference complex7rhx_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureMSTQRKSSR

Estimated binding specificities ?

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# IC=6.163 IC/col=0.560 n_of_columns=11 specificity:   
A |   9  70  24  24   9  16  24  24   0  96   0
C |   6   0  24  24   6  61  24  24   0   0   0
G |   6  13  24  24   6  13  24  24   0   0   0
T |  75  13  24  24  75   6  24  24  96   0  96
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updated Mon Dec 18 05:50:21 2023