6xg8_A : 3D-footprint complex

structure name	ISCTH4 TRANSPOSASE, PRE-CLEAVED COMPLEX, PCC
reference	Kosek et al. 'Embo 40 e105666 2021
experiment	X-ray (resolution=3.50, R-factor=0.222)
structural superfamily	Ribonuclease H-like;
sequence family	Transposase, Mutator family; MULE transposase domain;
multimeric complexes	6xg8_AB 6xgw_AB 6xgx_AB
redundant complexes	6xgw_A 6xgx_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6xg8_A interface=54,64,66,69,86,88,100,102,121,122,137,138,139,142,357,358,360, iitpekkelirnliseynitsakdlqealkdllgdtiqnmleaeldehlgyekYesteeaksnYrNgyTsktlkssvgqveidipRdRnaefepkivprYkRdiseienkiiamyargmsTReineqiqeiygfevSAEmvSkitdkilpeieewqkrplgevypivfidaihfsvkndgivgkkavyivlaidiegqkdvigiyvgenesskfwlsvlndlknrgvkdililcadalsgikdainaafpnteyqrcivhqirntlkyvsdkdrkefardlkriytapnekagydqmlevsekwekkypaamkswksnwdvicpffkyseelrkimyttntieslnssyrrinksrTVfPgdqsllksiylatvkitskwtmryknwglilgqlqimfegr
interface signature	YYNTRRYRTRSAESTVP

Estimated binding specificities ?

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# IC=18.074 IC/col=0.861 n_of_columns=21

specificity:

A |   2   2   0  73   0  96   0  94  73   3  24  24  24  24  10   2   0  96   0  73   0
C |   2  13   0  13  96   0  96   0   8  93  24  24  24  24   5   2   0   0  96   8  96
G |   5   2   0   5   0   0   0   2   7   0  24  24  24  24   8   5   0   0   0   7   0
T |  87  79  96   5   0   0   0   0   8   0  24  24  24  24  73  87  96   0   0   8   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  YAYTNCTTRTRGYTRTTGRGSTATEAST------------------------TGVCPG   L          +-----------------------6xg8_A    
                                                                       +--6 
  ----------------------------------------NGRGTGLGLCRG------           !  +-----------------------4ew0_A    
                                                                       ! 
  ------------RA--------------ITQTNAMG----------------------   L       !                           +5zjt_E    
                                                                     +-7            +--------------1 
  ------------RT--------------IAQTNA------------------------   L     ! !            !              +5lux_K    
                                                                     ! !          +-4 
  ------------RT--------------VAQTNA------------------------   L     ! !          ! !              +3lnq_A    
                                                                   +-8 +----------5 +--------------2 
  ----------------------------IAQCNAMG----------------------   L   ! !            !                +1b72_A    
                                                                   ! !            ! 
  ------------RA--------------IAQTNAMC----------------------   L   ! !            +---------------1puf_A    
                                                                 --9 ! 
  ------------------------------------KT--------------------   L   ! +----------------------------5ejk_E    
                                                                   ! 
  --------------------------------------LTNGRGTGLCLCRG------       !                           +4ofa_A    
                                                                   +---------------------------3 
  ----------------------------------------NGRGTGLGLCRG------                                   +4e9f_A

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updated Tue Dec 19 16:21:08 2023