interface graph thumbnail
legend  pdf

structure nameISCTH4 TRANSPOSASE, PRE-REACTION COMPLEX, PRC
referenceKosek et al. 'Embo 40 e105666 2021
experimentX-ray (resolution=3.50, R-factor=0.252)
structural superfamilyRibonuclease H-like;
sequence familyTransposase, Mutator family; MULE transposase domain;
multimeric complexes6xg8_AB 6xgw_AB 6xgx_AB
redundant complexes6xg8
reference complex6xg8_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYYNTRRYRTRSAESTVP

Estimated binding specificities ?

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# IC=16.890 IC/col=0.804 n_of_columns=21 specificity:   
A |   1   0   3   0  86   0  92  24  90  24   1  69  24  24  24   7   0   1  96   0  90
C |   6   1   1   0   1  96   1  24   1  24  95  11  24  24  24  15   0   6   0  96   4
G |  80   1   0   0   8   0   1  24   4  24   0  15  24  24  24  15   3   7   0   0   1
T |   9  94  92  96   1   0   2  24   1  24   0   1  24  24  24  59  93  82   0   0   1
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Mon Dec 18 19:16:33 2023