| structure name | HOMEOBOX TRANSCRIPTION FACTOR CDX1 BOUND TO METHYLATED DNA (Homeobox protein CDX-1) |
| reference | Morgunova et al. Science 356 ? 2017 |
| source | Homo sapiens |
| experiment | X-ray (resolution=3.23, R-factor=0.247) |
| structural superfamily | Homeodomain-like; |
| sequence family | Homeobox domain; |
| reference complex | 7q3o_C |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | YRIQN |
Estimated binding specificities ?
| contact |  |
A | 13 24 24 0 96 96 57 C | 13 24 24 0 0 0 13 G | 13 24 24 0 0 0 13 T | 57 24 24 96 0 0 13scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: CDX1 | ||
| GTTTAGA | PubMed | 5lux_K(1.05e-02) |
| TATAAAA | PubMed | 5lux_K(1.05e-02) |
Dendrogram of similar interfaces ?
matrix format--RART--------------VTKGNA--KA-- L +2lkx_A +-1 --KGRT--------------IAQCNAYA--RT L +------------3 +1nk2_P ! ! --RCRT--------------NT--NAITRG-- L +----7 +5zjt_B ! ! ------------------RCVACTNAQA---- L ! +-------------7xrc_C ! --RTRT--------------VAQTNA------ L +----8 +3lnq_A ! ! +-2 --RTRT--------------IAKGNA------ L ! ! +------4 +6m3d_C ! ! ! ! RC--RT--------------ITQCNAACRG-- L +-10 +---------6 +-6a8r_A ! ! ! ------------------RTVAITNAMCRG-- L ! ! +--------1yrn_A ! ! ----RA--------------YAQTNAAARG-- L +-12 +-----------------------6wig_A ! ! --------------YTVCKGDCKC-------- L ! ! +--------------------2qhb_A ! ! +----9 RT--RT--------------VAQTNA------ L ! ! ! ! +--1fjl_B +-13 +-11 +-----------------5 ----RT--------STVCKGDCRG-------- L ! ! ! +--1w0t_A ! ! ! RA--RT--------------VA--NAQT---- L -14 ! +-------------------------3d1n_M ! ! ----YTRTTGRGSTATEAST------------ L ! +---------------------------6xg8_A ! ----------------------KC--YCFAKC +----------------------------6p5a_B |
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updated Mon Dec 18 13:16:26 2023