7w7l_B : 3D-footprint complex

structure name	STRUCTURE OF NF-KB P52 HOMODIMER BOUND TO 13-MER A/T-CENTRIC P- SELECTIN KB DNA FRAGMENT (Nuclear factor NF-kappa-B p52 subunit)
reference	Meshcheryakov et al. 'To ? ? ?
source	Homo sapiens
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
sequence family	Rel homology domain RHD; IPT/TIG domain;
multimeric complexes	7w7l_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7w7l_B interface=19,21,22,25,29,188, tadgpylviveqpkqrgfRfRYgcEgpsHgglpgassekgrktyptvkicnyegpakievdlvthsdpprahahslvgkqcselgicavsvgpkdmtaqfnnlgvlhvtkknmmgtmiqklqrqrlrsrpqglteaeqreleqeakelkkvmdlsivrlrfsaflrasdgsfslplkpvisqpihdsKspgasnlkisrmdktagsvrggdevyllcdkvqkddievrfyeddengwqafgdfsptdvhkqyaivfrtppyhkmkierpvtvflqlkrkrggdvsdskqftyyp
interface signature	RRYEHK

Estimated binding specificities ?

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# IC=6.027 IC/col=1.004 n_of_columns=6

specificity:

A |  41   0   0   0   0  70
C |  27  96  96  96  96  13
G |  15   0   0   0   0   0
T |  13   0   0   0   0  13

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Dendrogram of similar interfaces ?

matrix format

  
  RGRGYA--EC----HGKG------   L                           +7w7l_B    
                                                       +-1 
  RGRGYACCEC--SAHGKG------   L                       +-4 +7cli_B    
                                                     ! ! 
  RGRGYTCCEC----HGKG------   L                   +---5 +1a3q_A    
                                                 !   ! 
  RCRCYC--EC----HCKT----RG   L               +---6   +1svc_P    
                                             !   ! 
  RGRGYTCTEC------RT------   L   +-----------7   +----1gji_A    
                                 !           ! 
  RGRGYTCCEC------KT------   L   !           !        +2v2t_A    
                                 !           +--------3 
  RGRG----EC------RGPTKT--   L --8                    ! +2ram_A    
                                 !                    +-2 
  RGRGYTCTECRT----RT--KA--   L   !                      +2o61_A    
                                 ! 
  RGRG----EGRG------------   L   +--------------------1bvo_A

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updated Fri Dec 23 06:50:38 2022