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structure nameTHE HOMING ENDONUCLEASE I-SCEI BOUND TO ITS DNA RECOGNITION REGION
(Intron-encoded endonuclease I-SceI)
referenceQuiocho et al. J.Mol.Biol. 334 685 2003
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.25, R-factor=0.235)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG DNA endonuclease family;
redundant complexes3ool 3oor
reference complex3c0w_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signaturePNYRRQEKRVQDYNNQNK

Estimated binding specificities ?

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# IC=18.212 IC/col=0.959 n_of_columns=19 specificity:   
A |   6   0  87   3   0   0  87  24  24  81   0  96   0   0   0   3  87  78   0
C |  72   0   3   6   0   0   3  24  24   3  96   0   0   0   0   3   3   6   6
G |   9   0   3  81  96  96   3  24  24   0   0   0  96  96  96   6   3   9   3
T |   9  96   3   6   0   0   3  24  24  12   0   0   0   0   0  84   3   3  87
scan!

Dendrogram of similar interfaces ?

matrix format
  
  PTNTYGRGRGQG--EC----KT--RG--VAQC------DTYCNT--------NCQC----------NGKG------------   L            +-------------1r7m_B    
                                                                                           +--------5 
  ----YTST----------EC--RG--RG----CC--ST--YG------------------YA--------CCKT--KG--TT   L   !        +-------------2qoj_Z    
                                                                                           ! 
  ----ST------EC--AT----YG--NA----CT----------------------RA--ET--RG----ATDT----TA--   L --6                    +-4lq0_A    
                                                                                           !               +----3 
  --------------------------------CC------------------------RT------KGRTVAEC--QT----   L   !               !    ! +4yit_A    
                                                                                           !               !    +-1 
  --------------------------------CTVA------------------------ST--DA--RGTC--KT--TG--   L   +---------------4      +5esp_A    
                                                                                                           ! 
  --------------------------------YC----------QARTRGEC------YA--KG--KG--RTWC--------   L                   !     +5t2o_A    
                                                                                                           +-----2 
  --------------------------------HT------------------------YT--QA--YT--RTWCST--ST--   L                         +5t8d_A    
                                                                                         

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updated Mon Dec 18 05:56:25 2023