interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF DNMT3A-DNMT3L IN COMPLEX WITH SINGLE CPG- CONTAINING DNA
(DNA CYTOSINE-5-METHYLTRANSFERASE 3A)
referenceZhang et al. Nature 554 387 2018
sourceHOMO SAPIENS
experimentX-ray (resolution=3.10, R-factor=0.213)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyC5 cytosinespecific DNA methylase 579;
multimeric complexes5yx2_AD 6brr_AD 6w89_AD 6w89_GJ 6w8b_AD 6w8b_HK 6w8d_AD 6w8j_AD
reference complex6w8b_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIVNPTRSNL

Estimated binding specificities ?

contactlogo
# IC=5.807 IC/col=0.968 n_of_columns=6 specificity:   
A |  13  96   0   0   0  57
C |  13   0   0  96  96  13
G |  54   0  96   0   0  13
T |  16   0   0   0   0  13
scan!

home
updated Mon Dec 18 15:06:32 2023