6w8d_AD : 3D-footprint complex

structure name	STRUCTURE OF DNMT3A (R882H) IN COMPLEX WITH CGT DNA
reference	Anteneh et al. 'Nat 11 2294 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6w8b_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w8d_A interface=87,88,89,90,208,210, ekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVNParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtittRsNsikqgkdqhfpvfmnekedilwctemervfgfpvhytdvsnmshlarqrllgrswsvpvirhlfaplkeyfacv > 6w8d_D interface=88,89,91,209, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtittRsnsikqgkdqhfpvfmnekedilwctemervfgfpvhytdvsnmshlarqrllgrswsvpvirhlfaplkeyfacv
interface signature	IVNPRN/IVPR

Estimated binding specificities ?

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# IC=7.844 IC/col=0.392 n_of_columns=20

specificity:

A |   0   0  24   0  14   7  24  24  24  24  24  24  24  24  24  53   0  24   0  60
C |   0   0  24   0  10  14  24  24  24  24  24  24  24  24  24  10  96  24  96  16
G |   0  96  24  96  12  14  24  24  24  24  24  24  24  24  24  19   0  24   0  10
T |  96   0  24   0  60  61  24  24  24  24  24  24  24  24  24  14   0  24   0  10

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updated Sat Dec 16 20:26:30 2023