6w8b_AD : 3D-footprint complex

structure name	STRUCTURE OF DNMT3A IN COMPLEX WITH CGA DNA
reference	Anteneh et al. 'Nat 11 2294 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6w8b_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w8b_A interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv > 6w8b_D interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv
interface signature	IVPTRSNQ/IVPTRSNQ

Estimated binding specificities ?

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# IC=9.830 IC/col=0.578 n_of_columns=17

specificity:

A |   1   0  89   0  24  24  24  24  24  24  24   0  96   0   0   0  51
C |   6   0   1   0  24  24  24  24  24  24  24  25   0  13  96  84  14
G |  83  96   0   0  24  24  24  24  24  24  24  57   0   0   0   0  25
T |   6   0   6  96  24  24  24  24  24  24  24  14   0  83   0  12   6

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updated Sat Dec 16 20:25:46 2023