6w8b_HK : 3D-footprint complex

structure name	STRUCTURE OF DNMT3A IN COMPLEX WITH CGA DNA
reference	Anteneh et al. 'Nat 11 2294 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6w8b_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w8b_H interface=88,89,91,204,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvRtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv > 6w8b_K interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv
interface signature	IVPRTRSNQ/IVPTRSNQ

Estimated binding specificities ?

readout + contact

# IC=10.290 IC/col=0.643 n_of_columns=16

specificity:

A |   0   0  96   9   7  24  24  24  24  24  24   9  73   0   0   0
C |   0   0   0   7  75  24  24  24  24  24  24   7   9   0  96  96
G |  96  96   0   7   7  24  24  24  24  24  24  73   7   0   0   0
T |   0   0   0  73   7  24  24  24  24  24  24   7   7  96   0   0

scan!

home
updated Sat Dec 16 20:26:08 2023