| structure name | STRUCTURE OF HUMAN BRN-5 TRANSCRIPTION FACTOR IN COMPLEX WITH CORTICOTROPHIN-RELEASING HORMONE GENE PROMOTER (POU domain, class 6, transcription factor 1) |
| reference | Pereira et al. J.Struct.Biol. 167 159 2009 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.51, R-factor=0.212) |
| structural superfamily | lambda repressor-like DNA-binding domains;Homeodomain-like; |
| sequence family | Pou domain Nterminal to homeobox domain; |
| multimeric complexes | 3d1n_IK 3d1n_MO |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | QSQSSRRRVNQ |
Estimated binding specificities ?
| readout + contact |  |
A | 70 6 90 96 96 24 20 96 0 70 C | 6 6 0 0 0 24 0 0 0 8 G | 6 1 0 0 0 24 12 0 0 6 T | 14 83 6 0 0 24 64 0 96 12scan! |
Dendrogram of similar interfaces ?
matrix formatQASTQASTSART----RA----RT--------VA--NAQT---- L +-----------------3d1n_M +-----8 ----------------RT----RT--------VAQTNA------ L ! +-----------------1fjl_B ! ------------------KG--RT--------IAQCNAYA--RT L ! +1nk2_P ! +---------------2 ----------------RC----RT--------ITQCNAACRG-- L ! ! ! +6a8r_A +-10 ! +-1 ------------------RC--RT--------NT--NAITRG-- ! ! ! +5zjt_B ! ! +---7 ----------------------RT--------VAQTNA------ L ! ! ! ! +-5hod_A ! ! ! ! +-------3 --STQATTCARGLTNT----------------------QTRC-- L ! ! ! ! ! +-1au7_A ! ! ! +------6 --------------------RC--RT------NCSTNARG---- L -11 +--9 ! +-1mnm_C ! ! +-------4 ----------------------RT--------NT--NAIARG-- L ! ! +-1b72_B ! ! --SGQATTCTRGLTNT---------------------------- L ! ! +--------7xrc_C ! +-----------5 ----------------------RT--STVCKGDCRG-------- L ! +--------1w0t_A ! ------------------------------RTVAITNAMCRG-- L +------------------------1yrn_A |
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updated Tue Dec 19 07:14:46 2023