| structure name | THE 2.1A CRYSTAL STRUCTURE OF S. AUREUS GYRASE COMPLEX WITH GSK299423 AND DNA (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A) |
| reference | Eggleston et al. Nature 466 935 2010 |
| source | STAPHYLOCOCCUS AUREUS |
| experiment | X-ray (resolution=2.10, R-factor=0.184) |
| structural superfamily | Type II DNA topoisomerase; |
| sequence family | DNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain; |
| multimeric complexes | 2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5npk_bd 6fm4_BD 7mvs_AB |
| redundant complexes | 5cdo 4plb 5cdq 5cdp 2xct 5cdn 5cdr 5cdm 4bul 5bs3 |
| reference complex | 5npk_d |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RKYSESI |
Estimated binding specificities ?
| contact |  |
A | 0 0 24 54 13 C | 96 0 24 13 13 G | 0 96 24 13 57 T | 0 0 24 16 13scan! |
Dendrogram of similar interfaces ?
matrix formatRGKT----------SAET------IC-------------- L +2xcs_B +----4 --KT----RC----AT--------IC--RG---------- L ! ! +2xkk_C ! +-3 --KA----RT----AAETRG----IC--RA---------- L ! +5eix_A +---7 --KA--DC--------------ECIGSG------------ L ! ! +-4fm9_A ! ! +-5 --KT----------SA------EGIGSC------------ ! +--6 +-3l4j_A +------------8 ! --KG----------AG--RT--ECIGAG------------ ! ! +--3qx3_B ! ! ----YA--RT----SA--------IG-------------- ! ! +5cdp_C +---9 ! +-1 ----YT--------ST----RA--IG-------------- ! ! +---------2 +5bs8_A ! ! ! ------------STSA--RA----IA-------------- +-10 ! +3rae_A ! ! ! --KT------------------------------------ ! ! +----------------------5bs8_D -11 ! ----------RCQG------SG------------------ ! +--------------------------4qlc_U ! ------------------------------NTATATSTRG L +----------------------------1dh3_C |
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updated Mon Dec 18 07:21:09 2023