interface graph thumbnail
legend  pdf

structure name1.98A STRUCTURE OF THIOPHENE1 WITH S.AUREUS DNA GYRASE AND DNA
(DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B,DNA GYRASE...)
referenceStavenger et al. 'Proc. 114 E4492 2017
sourceSTAPHYLOCOCCUS AUREUS
experimentX-ray (resolution=1.98, R-factor=0.155)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5npk_bd 6fm4_BD 7fvs_AB 7fvt_AB 7mvs_AB
redundant complexes2xcs_B 2xct_B 4bul_C 4plb_D 5bs3_D 5npp_D 6fm4_B 6z1a_B 7fvs_A 7fvt_A 7mvs_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKYSRI

Estimated binding specificities ?

readout + contactlogo
# IC=5.766 IC/col=0.641 n_of_columns=9 specificity:   
A |   0   0  24  54   0   0  24  24  16
C |  96   0  24  13   0   0  24  24  54
G |   0  96  24  16  96  96  24  24  13
T |   0   0  24  13   0   0  24  24  13
scan!

Dendrogram of similar interfaces ?

matrix format

home
updated Tue Dec 19 10:58:03 2023