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structure nameCRYSTAL STRUCTURE OF TFAM (MITOCHONDRIAL TRANSCRIPTION FACTOR A) BRIDGING TWO NON-SEQUENCE SPECIFIC DNA SUBSTRATES
(Transcription factor A, mitochondrial)
referenceGarcia-Diaz et al. 'Nucleic 50 322 2022
sourceHomo sapiens
experimentX-ray (resolution=2.84, R-factor=0.200)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
multimeric complexes3tq6_AB 6erp_ACF 6erp_BGJ 6erq_ACF 6erq_BGJ 6hb4_ADGJ 6hc3_ADGJ 7lbw_AB
reference complex3tq6_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYLSLTTIMKRYNVFPQL

Estimated binding specificities ?

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# IC=9.811 IC/col=0.363 n_of_columns=27 specificity:   
A |   0   0   0   4  24  24  24  12  24  24  24  24  24  24  24  24  24  24  24  24  72  24  24  84  96   4   4
C |   4  96   0  84  24  24  24   8  24  24  24  24  24  24  24  24  24  24  24  24  16  24  24   4   0   0   4
G |  92   0   0   4  24  24  24  60  24  24  24  24  24  24  24  24  24  24  24  24   4  24  24   4   0  92  84
T |   0   0  96   4  24  24  24  16  24  24  24  24  24  24  24  24  24  24  24  24   4  24  24   4   0   0   4
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updated Mon Dec 18 20:51:20 2023