interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE TRANSCRIPTIONAL REGULATOR CADR FROM P. PUTIDA IN COMPLEX WITH CADMIUM(II) AND DNA
(CADR)
referenceLiu et al. Proc.Natl.Acad.Sci.USA 116 20398 2019
sourcePSEUDOMONAS PUTIDA
experimentX-ray (resolution=2.71, R-factor=0.211)
structural superfamilyPutative DNA-binding domain;
sequence familyMerR, DNA binding; MerR family regulatory protein;
multimeric complexes6jgw_AB 6jgx_AB 6jni_CD 6jni_EF 6jyw_AB
redundant complexes6jgw_B 6jni_E 6jyw_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureERYRY

Estimated binding specificities ?

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# IC=4.434 IC/col=0.493 n_of_columns=9 specificity:   
A |  14  24  25   0  24  19  24   0   0
C |  62  24  48   1  24  19  24   0   0
G |   6  24   9   4  24  14  24  96   0
T |  14  24  14  91  24  44  24   0  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  EARTYARTYG   L                 +-----6jgx_B    
                   +-------------3 
  RGHTHC--YG   L   !             +-----1r8d_B    
                   ! 
  RGRTYT--RT   L --5                   +4r4e_B    
                   !         +---------1 
  RART------       !         !         +4r24_B    
                   +---------4 
  RGRTYT--KT   L             !        +7tea_B    
                             +--------2 
  RCRT------                          +7tec_A    
                 

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updated Tue Dec 19 13:20:49 2023