| structure name | HOMO SAPIENS CCCTC-BINDING FACTOR (CTCF) ZNF3-7 AND DNA COMPLEX STRUCTURE (Transcriptional repressor CTCF) |
| reference | Hashimoto et al. 'Mol. 66 711 2017 |
| source | Homo sapiens |
| experiment | X-ray (resolution=1.74, R-factor=0.171) |
| structural superfamily | beta-beta-alpha zinc fingers; |
| sequence family | Zinc finger, C2H2 type; |
| redundant complexes |  5t00_D
5t0u_D
5yef_J
8sss_A
8sst_D
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | TERYESKRDYKRQTRSDV |
Estimated binding specificities ?
| readout + contact |  |
A | 9 0 17 0 0 8 0 0 0 0 0 0 0 8 C | 0 96 0 96 96 69 96 96 0 0 96 0 0 19 G | 87 0 78 0 0 8 0 0 0 96 0 0 96 52 T | 0 0 1 0 0 11 0 0 96 0 0 96 0 17scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: CTCF | ||
| CCCTC | PubMed | 5kkq_D(1.05e-02), 5t00_D(1.00e-02) |
| CCCTCC | PubMed | 5kkq_D(1.86e-03), 5t00_D(1.77e-03) |
Dendrogram of similar interfaces ?
matrix format----------EC--SGKGRGDGYCKG--RG--QA----TC--------RASCDCVT L +-----------------------------5k5h_A ! --SA--MT--VT----NARG--ETTG------YG--ST------------------ ! +6e94_A ! +------------------1 CTSTQTLTITST--STHTRGRG--EA--RA----TTTGEC--RG----RG--ET-- L ! +---2 +5v3j_F ! ! ! KGWTKA--------HCHGRGTAACNA--KG-------------------------- L +-7 +--3 +------------------1tf6_A ! ! ! ! --------NGKT--WTKG----HTHG--RGTGTT--ACNA--KGRG---------- L ! ! +-4 +----------------------1tf3_A ! ! ! ! --------RGST--YGYC--QCTGSTRGYT-------------------------- ! ! +-5 +-------------------------4is1_C --8 ! ! ! --------------------QA--TC--RG--RG--YCRT---------------- L ! +-6 +--------------------------7txc_E ! ! --------QT--AG--KGRGRGDCKG------------------------------ L ! +---------------------------7n5w_A ! --------------------QGRGHT--MG--QG----LGLC----TTRG------ L +-----------------------------5yel_A |
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updated Tue Dec 19 10:49:43 2023