8sss_A : 3D-footprint complex

structure name	ZNFS 1-7 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 23MER (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=0.201)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	5kkq_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sss_A interface=13,15,16,19,44,69,70,72,75,79,98,101,104,126,128,129,132,154,157,184,186,187,190, tfqcelcsytcpRrSNldRhmkshtderphkchlcgrafrtvtLlrnhlnthtgtrphkcpdcdmafvTSgElvRhrrYkhthekpfkcsmcdyasvEvsKlkRhirshtgerpfqcslcsyasrDtYKlkRhmrthsgekpyecyicharftQsgTmkmhilqkhtenvakfhcphcdtviaRkSDlgVhlrkqhs
interface signature	RSNRLTSERYEKRDYKRQTRSDV

Estimated binding specificities ?

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# IC=15.770 IC/col=0.686 n_of_columns=23

specificity:

A |  24  19   1  34  13   0  96   7  12   0   0   2   0   7   8  20  36  24   0   8  96   4  12
C |  24  45  93  20  10  96   0   7  12   0   0   2  96   8  70  20  20  24   0   7   0   7  12
G |  24  16   1  22  63   0   0  74  60  96  96  90   0  74  10  20  20  24   0  74   0  81  60
T |  24  16   1  20  10   0   0   8  12   0   0   2   0   7   8  36  20  24  96   7   0   4  12

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updated Tue Dec 19 04:52:59 2023