8sst_D : 3D-footprint complex

structure name	ZNFS 1-7 OF CCCTC-BINDING FACTOR (CTCF) K365T MUTANT COMPLEXED WITH 23MER (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=2.19, R-factor=0.221)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	5kkq_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sst_D interface=13,16,19,44,69,70,72,75,79,98,104,126,128,129,132,154,157,184,186,187,190, tfqcelcsytcpRrsNldRhmkshtderphkchlcgrafrtvtLlrnhlnthtgtrphkcpdcdmafvTSgElvRhrrYkhthekpfkcsmcdyasvEvstlkRhirshtgerpfqcslcsyasrDtYKlkRhmrthsgekpyecyicharftQsgTmkmhilqkhtenvakfhcphcdtviaRkSDlgVhlrkqhsy
interface signature	RNRLTSERYERDYKRQTRSDV

Estimated binding specificities ?

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# IC=12.372 IC/col=0.538 n_of_columns=23

specificity:

A |  24  20  10   2  96  22  21  39  10   8   0  12   4   0   9   8   0   3  10  20   4  17  24
C |  24  34  13  90   0  30  21  19  13  70   0  60  88  96  67  70   0   5  63  20   2  15  24
G |  24  22  10   2   0  22  21  19  63  10  96  12   2   0   9  10   0  85  13  20  88  49  24
T |  24  20  63   2   0  22  33  19  10   8   0  12   2   0  11   8  96   3  10  36   2  15  24

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updated Tue Dec 19 04:53:09 2023