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structure nameCRYSTAL STRUCTURE OF THE HOMING ENDONUCLEASE I-CVUI IN COMPLEX WITH I- CREI TARGET (C1221) IN THE PRESENCE OF 2 MM MG REVEALING DNA NOT CLEAVED
(DNA ENDONUCLEASE I-CVUI)
referenceLopezMendez et al. J.Biol.Chem. 290 28727 2015
sourceCHLORELLA VULGARIS
experimentX-ray (resolution=2.50, R-factor=0.222)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes5a72_AB 5a74_AB 5a77_AB 5a78_AB
redundant complexes5a72
reference complex5a74_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureCQVRDYQRFRRNDMEK

Estimated binding specificities ?

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# IC=12.586 IC/col=1.049 n_of_columns=12 specificity:   
A |   5  79   5   0  96   0   0   5  79   1   5   0
C |   5   5  79   0   0  96   0   1   7   5   7   0
G |   7   5   5  96   0   0  96   0   5   0   0  96
T |  79   7   7   0   0   0   0  90   5  90  84   0
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Dendrogram of similar interfaces ?

matrix format



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updated Mon Dec 18 11:51:00 2023