4gdf_A : 3D-footprint complex

structure name	A CRYSTAL STRUCTURE OF SV40 LARGE T ANTIGEN (Large T antigen)
reference	Chang et al. 'Cell 3 1117 2013
source	Simian virus 40
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;Origin of replication-binding domain, RBD-like;
sequence family	Polyomavirus large T antigen Cterminu; Origin of replication binding protein;
multimeric complexes	4gdf_AB 4gdf_EF
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4gdf_A interface=21,22,23,24,25,74,137,140,202,383, kvedpkdfpsellsflshavFSNRTlacfaiyttkekaallykkimekysvtfisrhnsynhnilffltphrhRvsainnyaqklctfsflickgvnkeylmysaltrdpfsvieeslpgglkehdfnpeeaeetkQvsWklvteyametkcddvllllgmylefqysfemclkcikkeqpshykyhekhyanaaifadskNqkticqqavdtvlakkrvdslqltreqmltnrfndlldrmdimfgstgsadieewmagvawlhcllpkmdsvvydflkcmvynipkkrywlfkgpidsgkttlaaallelcggkalnvnlpldrlnfelgvaidqflvvfedvkgtggesrdlpsgqginnldnlrdyldgsvkvnlekkHlnkrtqifppgivtmneysvpktlqarfvkqidfrpkdylkhclersefllekriiqsgialllmliwyrpvaefaqsiqsrivewkerldkefslsvyqkmkfnvamgigvld
interface signature	FSNRTRQWNH

Estimated binding specificities ?

contact

# IC=6.407 IC/col=0.915 n_of_columns=7

specificity:

A |  72   0  72   8   0   0   8
C |   8   0   8   8   0  96  72
G |   8  96   8  80  96   0   8
T |   8   0   8   0   0   0   8

scan!

Dendrogram of similar interfaces ?

matrix format

  
  FGSANGRGTC----------RGQGWANTHC   L                +-----------------4gdf_A    
                                             +------1 
  ----------------------------HT           +-2      +-----------------2gxa_L    
                                           ! ! 
  --SANGKGTC----------RG--------   L     +-3 +------------------------3qfq_B    
                                         ! ! 
  --SGNGKGTC----------RG--------   L   +-4 +--------------------------4fb3_A    
                                       ! ! 
  NT--KTTTTC--------------------     --5 +---------------------------1ksy_A    
                                       ! 
  ----------NCKGCAYTRC----------   L   +----------------------------1jj4_B

home
updated Tue Dec 19 08:50:54 2023