4gdf_EF : 3D-footprint complex

structure name	A CRYSTAL STRUCTURE OF SV40 LARGE T ANTIGEN
reference	Chang et al. 'Cell 3 1117 2013
source	Simian virus 40
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;Origin of replication-binding domain, RBD-like;
reference complex	4gdf_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4gdf_E interface=21,22,23,24,25,74,137,140,202,383, kvedpkdfpsellsflshavFSNRTlacfaiyttkekaallykkimekysvtfisrhnsynhnilffltphrhRvsainnyaqklctfsflickgvnkeylmysaltrdpfsvieeslpgglkehdfnpeeaeetkQvsWklvteyametkcddvllllgmylefqysfemclkcikkeqpshykyhekhyanaaifadskNqkticqqavdtvlakkrvdslqltreqmltnrfndlldrmdimfgstgsadieewmagvawlhcllpkmdsvvydflkcmvynipkkrywlfkgpidsgkttlaaallelcggkalnvnlpldrlnfelgvaidqflvvfedvkgtggesrdlpsgqginnldnlrdyldgsvkvnlekkHlnkrtqifppgivtmneysvpktlqarfvkqidfrpkdylkhclersefllekriiqsgialllmliwyrpvaefaqsiqsrivewkerldkefslsvyqkmkfnvamgigvld > 4gdf_F interface=23,24,25,72,74,383, kvedpkdfpsellsflshavfsNRTlacfaiyttkekaallykkimekysvtfisrhnsynhnilffltphRhRvsainnyaqklctfsflickgvnkeylmysaltrdpfsvieeslpgglkehdfnpeeaeetkqvswklvteyametkcddvllllgmylefqysfemclkcikkeqpshykyhekhyanaaifadsknqkticqqavdtvlakkrvdslqltreqmltnrfndlldrmdimfgstgsadieewmagvawlhcllpkmdsvvydflkcmvynipkkrywlfkgpidsgkttlaaallelcggkalnvnlpldrlnfelgvaidqflvvfedvkgtggesrdlpsgqginnldnlrdyldgsvkvnlekkHlnkrtqifppgivtmneysvpktlqarfvkqidfrpkdylkhclersefllekriiqsgialllmliwyrpvaefaqsiqsrivewkerldkefslsvyqkmkfnvamgigvld
interface signature	FSNRTRQWNH/NRTRRH

Estimated binding specificities ?

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# IC=10.273 IC/col=0.856 n_of_columns=12

specificity:

A |   7   0   0   0   7   0   7  24  24   0   0   7
C |   7   0  96  82   9  96   1  24  24   0  96   7
G |  73  96   0   7   7   0   0  24  24  96   0   7
T |   9   0   0   7  73   0  88  24  24   0   0  75

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updated Fri Dec 15 19:11:31 2023