3qfq_B : 3D-footprint complex

structure name	ASYMMETRIC ASSEMBLY OF MERKEL CELL POLYOMAVIRUS LARGE T-ANTIGEN ORIGIN BINDING DOMAINS AT THE VIRAL ORIGIN (Large T antigen)
reference	Harrison et al. J.Mol.Biol. 409 529 2011
source	Merkel cell polyomavirus
experiment	X-ray (resolution=2.90, R-factor=0.228)
structural superfamily	Origin of replication-binding domain, RBD-like;
sequence family	Origin of replication binding protein;
multimeric complexes	3qfq_ABE
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3qfq_B interface=21,22,23,24,72, tpvptdfpidlsdylshavySNKTvscfaiyttsdkaielydkiekfkvdfksrhacelgcillfitlskhRvsaiknfcstfctisflickgvnkmpemynnlckppykllqenkplln
interface signature	SNKTR

Estimated binding specificities ?

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# IC=5.807 IC/col=0.968 n_of_columns=6

specificity:

A |   0  54   0  13   0   0
C |   0  13   0  13  96   0
G |  96  16  96  57   0   0
T |   0  13   0  13   0  96

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --SANGKGTC------------RG----------------------   L                               +3qfq_B    
                                                                 +-----------------1 
  FGSANGRGTC------------RG----------------------   L     +-------2                 +4gdf_A    
                                                         !       ! 
  ------------------------FTKAHGIAEAACKC----NC--       +-3       +-----------------6wdz_D    
                                                       ! ! 
  ----------KATGTGSGVGFA------RA--ECACKCSCTA----   L --4 +-------------------------5tkz_B    
                                                       ! 
  --------------------------------------------YG       +--------------------------7rbh_A

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updated Tue Dec 19 08:04:29 2023