structure nameHUMAN MUTSBETA COMPLEXED WITH AN IDL OF 4 BASES (LOOP4) AND ADP
(DNA MISMATCH REPAIR PROTEIN MSH3)
referenceNat.Struct.Mol.Biol. 19 72 2012
sourceHOMO SAPIENS
experimentX-ray (resolution=3.09, R-factor=0.229)
structural superfamilyDNA repair protein MutS, domain III;P-loop containing nucleoside triphosphate hydrolases;
sequence familyMutS domain V; MutS domain I; MutS domain II; MutS domain III;
multimeric complexes3thw_AB 3thx_AB 3thy_AB 3thz_AB 8olx_AB 8oma_AB
reference complex3thx_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYKHS

Estimated binding specificities ?

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# IC=5.766 IC/col=0.222 n_of_columns=26 specificity:   
A |   0   0  24  24  24  24  24  24  24  24  24  24  24  24  54  16  24  24  24  24  24   0  24  24  24  96
C |  96  96  24  24  24  24  24  24  24  24  24  24  24  24  13  13  24  24  24  24  24   0  24  24  24   0
G |   0   0  24  24  24  24  24  24  24  24  24  24  24  24  13  13  24  24  24  24  24  96  24  24  24   0
T |   0   0  24  24  24  24  24  24  24  24  24  24  24  24  16  54  24  24  24  24  24   0  24  24  24   0
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updated Mon Dec 18 09:16:40 2023