3thz_AB : 3D-footprint complex

structure name	HUMAN MUTSBETA COMPLEXED WITH AN IDL OF 6 BASES (LOOP6) AND ADP
reference	Nat.Struct.Mol.Biol. 19 72 2012 X-RAY DIFFRACTION
source	HOMO SAPIENS
experiment	X-ray (resolution=4.30, R-factor=?)
structural superfamily	DNA repair protein MutS, domain III;P-loop containing nucleoside triphosphate hydrolases;
reference complex	3thx_B 8ag6_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3thz_A interface=31,32,69,71, lesaaevgfvrffqgmpekptttvrlfdrgDFytahgedallaarevfktqgvikymgpagaknlqsvVlSkmnfesfvkdlllvrqyrvevyknraskendwylaykaspgnlsqfedilfgnndmigvvgvkmsavdgqrqvgvgyvdsiqrklglcefpdndqfsnlealliqigpkecvlpggetagdmgklrqiiqrggiliterkkadfstkdiyqdlnrllkgkkgeqmnsavlpemenqvavsslsavikflellsddsnfgqfelttfdfsqymkldiaavralnlfqgssqslaallnkcktpqgqrlvnqwikqplmdknrieerlnlveafvedaelrqtlqedllrrfpdlnrlakkfqrqaanlqdcyrlyqginqlpnviqalekhegkhqklllavfvtpltdlrsdfskfqemiettldmdqvenheflvkpsfdpnlselreimndlekkmqstlisaardlgldpgkqikldssagyyfrvtckeekvlrnnknfstvdiqgvkftnskltslneeytknkteyeeaqdaivkeivnissgyvepmqtlndvlaqldavvsfahvsngapvpyvrpailekgqgriilkasrhacvevqdeiafipndvyfekdkqmfhiitgpnmggkstyirqtgvivlmaqigcfvpcesaevsivdcilarvglkgvstfmaemletasilrsatkdsliiidelgrgtstydgfglawaiseyiatkigafcmfathfheltalanqiptvnnlhvtaltteetltmlyqvkkgvcdqsfgihvaelanfpkhviecakqkaleleefqmepaakkcylereqgekiiqeflskvkqmpftemseenitiklkqlkaeviaknnsfvneiisri > 3thz_B interface=30,31,62, sksiytplelqyiemkqqhkdavlcvecgYKyrffgedaeiaarelniychldhnfmtasiPthrlfvhvrrlvakgykvgvvkqtetaalkaigdnrsslfsrkltalytkstligedvnptdtstsyllcisenkkkkgnifigivgvqpatgevvfdsfqdsasrseletrmsslqpvelllpsalseqtealihratsvsvqddrirvermdniyfeyshafqavtefyakgivnlekpvicslaaiikylkefnlekmlskpenfkqlsskmefmtingttlrnleilqnqtdmktkgsllwvldhtktsfgrrklkkwvtqpllklreinarldavsevlhsessvfgqienhlrklpdierglcsiyhkkcstqefflivktlyhlksefqaiipavnshiqsdllrtvileipellspvehylkilneqaakvgdktelfkdlsdfplikkrkdeiqgvideirmhlqeirkilknpsaqyvtvsgqefmieiknsavsciptdwvkvgstkavsrfhspfivenyrhlnqlreqlvldcsaewldflekfsehyhslckavhhlatvdcifslakvakqgdycrptvqeerkivikngrhpvidvllgeqdqyvpnntdlsedservmiitgpnmggkssyikqvalitimaqigsyvpaeeatigivdgiftrmgaagrstfmeeltdtaeiirkatsqslvildelgrgtsthdgiaiayatleyfirdvksltlfvthyppvceleknyshqvgnyhmgflvfvtflyqitrgiaarsyglnvakladvpgeilkkaahkskeleglintkrkrlkyfaklwtmhnaqdlqkwt
interface signature	DFVS/YKP

Estimated binding specificities ?

contact

# IC=3.101 IC/col=0.443 n_of_columns=7

specificity:

A |  13  24  96  24  16  24  96
C |  54  24   0  24  54  24   0
G |  16  24   0  24  13  24   0
T |  13  24   0  24  13  24   0

scan!

home
updated Fri Dec 15 17:00:29 2023