interface graph thumbnail
legend  pdf

structure nameHUMAN MUTSBETA COMPLEXED WITH AN IDL OF 3 BASES (LOOP3) AND ADP
(DNA MISMATCH REPAIR PROTEIN MSH3)
referenceNat.Struct.Mol.Biol. 19 72 2012 X-RAY DIFFRACTION
sourceHOMO SAPIENS
experimentX-ray (resolution=2.70, R-factor=0.212)
structural superfamilyDNA repair protein MutS, domain III;P-loop containing nucleoside triphosphate hydrolases;
sequence familyMutS domain V; MutS domain I; MutS domain II; MutS domain III;
multimeric complexes3thw_AB 3thx_AB 3thy_AB 3thz_AB 8olx_AB 8oma_AB
redundant complexes3thw_B 3thy_B 8olx_B 8om9_B 3thz 8oma
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  --YGKA------SAPA                    +-----3thx_B    
                         +------------1 
  MGDAFGTT--MC--PT       !            +-----1wb9_A    
                       --4 
  VCKCFGETMT----PG       !       +----------2o8b_B    
                         +-------3 
  ----FGET--------               !    +-----1ewq_A    
                                 +----2 
  --DGFG------VGSG                    +-----3thx_A    
                       

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updated Tue Dec 19 08:11:02 2023