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structure nameI-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY (-8G)
(MSO-8G)
referenceStoddard et al. 'Nucleic 38 5601 2010
sourceSYNTHETIC CONSTRUCT
experimentX-ray (resolution=2.30, R-factor=0.249)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes1m5x_AB 2fld_AB 3ko2_AB 3ko2_FG 3mip_AB 3mis_AB
reference complex2fld_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYKERDYQRIRRDIY

Estimated binding specificities ?

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# IC=12.429 IC/col=1.130 n_of_columns=11 specificity:   
A |  13   0  96   0   0  96   0   0   0   0  13
C |  16  96   0   0   0   0  96   0   0  96  16
G |  54   0   0  96  96   0   0  96   0   0  54
T |  13   0   0   0   0   0   0   0  96   0  13
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updated Mon Dec 18 08:32:20 2023