| structure name | CRYSTAL STRUCTURE OF C/EBPBETA BZIP HOMODIMER V285A MUTANT BOUND TO A HIGH AFFINITY DNA FRAGMENT (CCAATenhancer-binding protein beta) |
| reference | Inoue-Bungo et al. 'To ? ? ? |
| source | Homo sapiens |
| experiment | X-ray (resolution=1.80, R-factor=0.232) |
| structural superfamily | Leucine zipper domain; |
| sequence family | Basic region leucine zipper; bZIP transcription factor; |
| multimeric complexes | 1gtw_AB 1gu4_AB 1gu5_AB 1h88_ABC 1h89_ABC 1h8a_ABC 1hjb_ABC 1hjb_DEF 1io4_ABC 2e42_AB 2e43_AB 6mg1_AB 6mg2_AB 6mg3_AB 7l4v_AB 7upz_AB |
| redundant complexes | 1hjb 2e43 1h89 1h88 1gu4 1io4 1h8a 1gu5 1gtw |
| reference complex | 6mg1_B |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RNNAASR |
Estimated binding specificities ?
| readout + contact |  |
A | 6 7 5 30 C | 7 14 6 57 G | 7 0 75 5 T | 76 75 10 4scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: C/EBPBETA | ||
| CAATT | PubMed | 1gtw_AB(4.33e-03), 1gu4_AB(4.06e-03), 2e42_AB(2.94e-03), ... (total=7) |
| CCAAT | PubMed | 1gtw_AB(4.33e-03), 1gu4_AB(4.06e-03), 1gu5_AB(6.59e-03), ... (total=8) |
Dendrogram of similar interfaces ?
matrix format----RA--NANCATAT--STRG L +2e42_B +-4 RGQGNARTAGQT--FTRG---- L ! +1gd2_F +--7 --------NCRTATAT--STRG L ! ! +1t2k_D ! +--2 ----RC--NANCAAVT----RG L ! +1nwq_A --8 --------NT--ATAT--STRC L ! +1jnm_A ! +-3 --------NCRTATAT--STRG L ! +-5 +1dh3_A ! ! ! --------NC--AAAT----RT L +---6 +1a02_F ! --------NCTT--AT----RG L ! +2dgc_A +-1 --------NT--ATAT--STRA L +2c9l_Y |
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updated Mon Dec 18 06:40:20 2023