interface graph thumbnail
legend  pdf

structure nameTERNARY COMPLEX OF STAPHYLOCOCCUS AUREUS DNA GYRASE WITH AMK12 AND DNA
referenceStevenson et al. 'Nat 12 150 2021
experimentX-ray (resolution=2.30, R-factor=0.181)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5npk_bd 6fm4_BD 7mvs_AB
reference complex5npk_d
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKYSRI

Estimated binding specificities ?

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# IC=3.768 IC/col=0.538 n_of_columns=7 specificity:   
A |  52  24   8  11  24   0   0
C |  27  24  52   8  24  96   0
G |  17  24  26   8  24   0  96
T |   0  24  10  69  24   0   0
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updated Mon Dec 18 19:25:06 2023