6p0c_A : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

Dendrogram of similar interfaces ?

matrix format

structure name	HUMAN DNA LIGASE 1 BOUND TO AN ADENYLATED, HYDROXYL TERMINATED DNA NICK IN EDTA (DNA ligase 1)
reference	Schellenberg et al. 'Nat 10 5431 2019
source	Homo sapiens
experiment	X-ray (resolution=1.55, R-factor=0.132)
structural superfamily	ATP-dependent DNA ligase DNA-binding domain;DNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;
sequence family	ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal re;
redundant complexes	1x9n_A 6p09_A 6p0a_A 6p0b_A 6p0d_A 6p0e_A 6q1v_A 7kr3_A 7kr4_A 7l34_A 7l35_A 7sum_A 7sx5_A 7sxe_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6p0c_A interface=46,287,376,384,511,512,539,612,613, sndpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsaRlrmvetlsnllrsvvalsppdllpvlylslnhlgppqqglelgvgdgvllkavaqatgrqlesvraeaaekgdvglvaensrstqrlmlppppltasgvfskfrdiarltgsastakkidiikglfvacrhsearfiarslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeqgmilkqtfcevpdldriipvllehglerlpehcklspgiplkpmlaHptrgisevlkrfeeaaftceykydgqraqihaleggevkifsrnqedntgkypdiisripkiklpsvtsfildteavawdrekkqiqpFqvlttrkRkevdaseiqvqvclyafdliylngeslvreplsrrrqllrenfvetegefvfatsldtkdieqiaefleqsvkdsceglmvktldvdatyeiakrshnwlklkkdyldgvgdtldlvvigaylgrgKRagryggfllasydedseelqaicklgTgfsdeeleehhqslkalvlpsprpyvridgavipdhwldpsavwevkcadlslspiypaarglvdsdkgislRFprfirvredkqpeqattsaqvaclyrkqs

  
  RTHTFT------RCKGTT--FG--   L                       +-----6p0c_A    
                                               +-----3 
  YC----FT----------RCFG--                     !     !  +--3l2p_A    
                                               !     +--1 
  ----------------ST--FG--            +--------5        +--6bkg_A    
                                      !        ! 
  --------NG--------FGLGIT            !        !      +----6dt1_A    
                                 +----6        +------2 
  ----------MG----SA--FC--       !    !               +----6rar_I    
                                 !    ! 
  --------------------QT--     --7    !        +-----------6iml_A    
                                 !    +--------4 
  ----FG------LCKGTA--FC--       !             +-----------6gdr_A    
                                 ! 
  ----------------TA--FG--       +-------------------------2q2t_A

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updated Tue Dec 19 14:00:28 2023