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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


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updated Mon Dec 18 17:36:16 2023
structure nameHUMAN DNA LIGASE 1 (E592R) BOUND TO AN ADENYLATED, HYDROXYL TERMINATED DNA NICK
(DNA ligase 1)
referenceSchellenberg et al. 'Nat 10 5431 2019
sourceHomo sapiens
experimentX-ray (resolution=1.85, R-factor=0.164)
structural superfamilyATP-dependent DNA ligase DNA-binding domain;DNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;
sequence familyATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal re;
reference complex6p0c_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence