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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


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updated Mon Dec 18 20:46:41 2023
structure nameHUMAN DNA LIGASE 1(E346A/E592A) BOUND TO A BULGED DNA SUBSTRATE
(DNA ligase 1)
referenceWilliams et al. 'Nat 12 482 2021
sourceHomo sapiens
experimentX-ray (resolution=2.78, R-factor=0.197)
structural superfamilyATP-dependent DNA ligase DNA-binding domain;DNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;
sequence familyATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal re;
reference complex6p0c_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence