interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYSTAL STRUCTURE OF MINICHROMOSOME MAINTENANCE PROTEIN MCM/DNA COMPLEX
referenceEnemark et al. 'Nat 10 3117 2019
experimentX-ray (resolution=3.15, R-factor=0.191)
structural superfamilyNucleic acid-binding proteins;P-loop containing nucleoside triphosphate hydrolases;
sequence familyMCM2/3/5 family; ATPase family associated with various cellul;
multimeric complexes6mii_ABCDEF
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  ------------------------------------------------------ETKT--YT                                     +--6mii_F    
                                                                                                   +-3 
  ----------------------------------------------------RT--------                                 +-6 +--6xtx_7    
                                                                                                 ! ! 
  ------------------------------------------------------------LT                               +-7 +---6xtx_4    
                                                                                               ! ! 
  ------------------------------------------------------------WT                         +-----8 +----6u0m_2    
                                                                                         !     ! 
  ----------------------------------------------------KT----RT--                         !     +-----6raw_5    
                                                                                    +---10  
  ----------------------------------------------------KT--------                    !    !         +-6sko_7    
                                                                                    !    !       +-1 
  --------------------------------------------------VT--------YT                    !    +-------5 +-6sko_6    
                                                                                +--11            ! 
  ------------------------------------------------------------WT                !   !            +---6sko_2    
                                                                                !   !  
  ----------------------------------------------------RT--------                !   !            +---6u0m_6    
                                                                             +-12   !       +----4 
  ----------------------------------------------------RT--------             !  !   +-------9    +---6raw_6    
                                                                             !  !           ! 
  ----------------------------------------------------RT--------       +----13  !           +--------6xtx_5    
                                                                       !     !  !  
  ------------------------------------------------------------FT       !     !  +--------------------6sko_5    
                                                                     -14     !  
  RTETKT------RTMT--RTFT----------------RT----------------------   L   !     +-----------------------4pog_H    
                                                                       !  
  RTLTKTSTPTST----------------------NT--KT----------------------   L   !                          +--2ccz_A    
                                                                       +--------------------------2 
  ----------------TT--WTRTITYTETRTWT--YT--NTNTMTQTLT------------   L                              +--6irq_A    
                                                                     

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updated Fri Dec 23 00:08:16 2022