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structure nameCRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN MEP DR1 RESPONSE ELEMENT, PH 4.2
(Retinoic acid receptor RXR-alpha)
referencePoussin-Courmontagne et al. 'Mol. 481 44 2019
sourceHomo sapiens
experimentX-ray (resolution=2.10, R-factor=0.181)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1by4_BC 1dsz_AB 1r0n_AB 1ynw_AB 2nll_AB 4cn2_CD 4cn3_AD 4cn3_BC 4cn5_AB 4cn7_AB 4cn7_EF 6fbq_AB 6fbr_AB 6xwg_CD 6xwh_CD
reference complex6fbq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureMEKKRR

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |  16   0  57  96   0
C |  13   0  13   0  96
G |  13  96  13   0   0
T |  54   0  13   0   0
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updated Mon Dec 18 15:09:07 2023