interface graph thumbnail
legend  pdf

structure nameTRANSCRIPTIONAL REPRESSOR, COUR, BOUND TO A 23-MER DNA DUPLEX
(Transcriptional regulator, MarR family)
referenceCogan et al. 'J. 293 11727 2018
sourceRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) / Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
experimentX-ray (resolution=2.85, R-factor=0.218)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes6c2s_AD 6c2s_BC
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLRPNVR

Estimated binding specificities ?

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# IC=6.338 IC/col=0.704 n_of_columns=9 specificity:   
A |  73   0  24  24   7   9  75   0  96
C |   7   0  24  24   7   7   7   0   0
G |   9   0  24  24   7   7   7   0   0
T |   7  96  24  24  75  73   7  96   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----LTRTPTNA--VT----------RT   L                              +-6c2s_C    
                                                  +-------------3 
  ----TT--PTTC--STNT--------RT   L                !             ! +4lln_I    
                                                  !             +-2 
  --NGLTKTPTST--TT--------RTRT   L         +------5               ! +7el3_B    
                                           !      !               +-1 
  --ET--RGTCTG--STRG--------KT   L         !      !                 +6q2b_B    
                                         +-6      ! 
  ------RGTCTA----RGNT------RT   L       ! !      +---------------4fx4_B    
                                         ! ! 
  ----TC--KTTCKGTCHT--ST------   L     +-7 +----------------------7ve5_B    
                                       ! ! 
  ----------------------YGRG--         ! !                +-------4wcg_A    
                                     +-8 +----------------4 
  ----SGRGPT----SGRG----------   L   ! !                  +-------7bhy_A    
                                   --9 ! 
  ----------------------YG----       ! +--------------------------3eyi_B    
                                     ! 
  RA--------------------------       +----------------------------6b6h_I    
                                   

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updated Tue Dec 19 12:22:20 2023