interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD5-MH1/PALINDROMIC SBE DNA COMPLEX
(Mothers against decapentaplegic homolog 5)
referenceWang et al. 'Nucleic 43 9051 2015
sourceMus musculus
experimentX-ray (resolution=3.05, R-factor=0.224)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
multimeric complexes3kmp_AB 5x6g_AB 5x6m_AB 5x6m_EF 6fzs_AB 6fzt_AB
redundant complexes5x6h 5x6m
reference complex6fzs_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRQHK

Estimated binding specificities ?

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# IC=5.766 IC/col=0.961 n_of_columns=6 specificity:   
A |  13  96   0  54   0  96
C |  13   0   0  13  96   0
G |  16   0  96  13   0   0
T |  54   0   0  16   0   0
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Dendrogram of similar interfaces ?

matrix format
  
  --RGQAHTKG   L                 +--5x6g_A    
                   +-------------2 
  DCRGQC--KG   L   !             +--6tbz_A    
                 --3 
  ----QC--KG       !                +5mey_A    
                   +----------------1 
  --RGQC--KG   L                    +5nm9_A    
                 

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updated Mon Dec 18 13:54:03 2023