5hf7_A : 3D-footprint complex

structure name	TDG ENZYME-SUBSTRATE COMPLEX (GT mismatch-specific thymine DNA glycosylase)
reference	Pozharski et al. 'Nucleic 44 10248 2016
source	Homo sapiens
experiment	X-ray (resolution=1.54, R-factor=0.187)
structural superfamily	Uracil-DNA glycosylase-like;
sequence family	Uracil DNA glycosylase superfamily;
multimeric complexes	2rba_AB 3ufj_AB 3uo7_AB 3uob_AB
redundant complexes	6u16 6u15 5ff8 5t2w 6u17
reference complex	4z47_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5hf7_A interface=52,94,95,168,169,170,171,172, kvdrfngvseaelltktlpdiltfnldiviiginpglmaaykghhypgpgnHfwkclfmsglsevqlnhmddhtlpgkygigftnmverttpgSKdlsskefreggrilvqklqkyqpriavfngkciyeifskevfgvkvknlefglqphkipdtetlcyvmpsssARCAQfpraqdkvhyyiklkdlrdqlkgie
interface signature	HSKARCAQ

Estimated binding specificities ?

contact

# IC=2.655 IC/col=0.664 n_of_columns=4

specificity:

A |  74   0   7  49
C |   7   0   7  17
G |   7  96   8  15
T |   8   0  74  15

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --RA--RCQTNTTC----   L            +-----------2dp6_A    
                              +-----1 
  ------------RG----       +--2     +-----------6iod_A    
                           !  ! 
  KT--TT--------RA--     --3  +-----------------4yig_E    
                           ! 
  ------PG--------NG       +--------------------1oe4_B

home
updated Mon Dec 18 12:52:40 2023