interface graph thumbnail
legend  pdf

structure nameTRANSCRIPTION FACTOR-DNA COMPLEX
(Signal transducer and activator of transcription 6)
referenceOuyang et al. Proc.Natl.Acad.Sci.USA 113 13015 2016
sourceHomo sapiens
experimentX-ray (resolution=3.20, R-factor=0.211)
structural superfamilyp53-like transcription factors;SH2 domain;STAT;
sequence familySTAT protein, DNA binding domain; STAT protein, allalpha domain; SH2 domain;
multimeric complexes4y5w_AC 4y5w_BD 5d39_AC 5d39_BD
reference complex4y5w_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVHNQ

Estimated binding specificities ?

contactlogo
# IC=2.635 IC/col=0.659 n_of_columns=4 specificity:   
A |   0   9  67  67
C |   0   9   9  11
G |  96  67   9   9
T |   0  11  11   9
scan!

home
updated Mon Dec 18 12:26:38 2023