interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF E43A ISCR MUTANT BOUND TO ITS PROMOTER
(HTH-type transcriptional regulator IscR)
referenceRajagopalan et al. Nat.Struct.Mol.Biol. 20 740 2013
sourceEscherichia coli
experimentX-ray (resolution=2.99, R-factor=0.233)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyTranscriptional regulator;
multimeric complexes4chu_AB 4hf1_AB 4hf2_AB
reference complex4hf1_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSSYQRP

Estimated binding specificities ?

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# IC=6.080 IC/col=0.676 n_of_columns=9 specificity:   
A |  78  54  72  24  24  78   0  96   6
C |   6  12   0  24  24   6   0   0  90
G |   6   6  18  24  24   6   0   0   0
T |   6  24   6  24  24   6  96   0   0
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updated Mon Dec 18 10:28:59 2023