4bul_C : 3D-footprint complex

structure name	NOVEL HYDROXYL TRICYCLICS (E.G. GSK966587) AS POTENT INHIBITORS OF BACTERIAL TYPE IIA TOPOISOMERASES (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)
reference	Rittenhouse et al.
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=2.60, R-factor=0.145)
structural superfamily	Type II DNA topoisomerase;
sequence family	DNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes	2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5npk_bd 6fm4_BD 7mvs_AB
reference complex	5npk_d
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4bul_C interface=45,206,265,266,273,303,356, gkladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavynernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvRmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql
interface signature	KYSSRRI

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# IC=3.868 IC/col=0.483 n_of_columns=8

A |  19  24  24   8   8  24   0   0
C |   8  24  24  62   8  24  96   0
G |  26  24  24  26   8  24   0  96
T |  43  24  24   0  72  24   0   0

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updated Mon Dec 18 09:50:05 2023