3zql_B : 3D-footprint complex

structure name	DNA-BOUND FORM OF TETR-LIKE REPRESSOR SIMR (PUTATIVE REPRESSOR SIMREG2)
reference	Schumacher et al. 'Nucleic 39 9433 2011
source	STREPTOMYCES ANTIBIOTICUS
experiment	X-ray (resolution=2.99, R-factor=0.212)
structural superfamily	Tetracyclin repressor-like, C-terminal domain;Homeodomain-like;
sequence family	Bacterial regulatory proteins, tetR family; Tetracyclin repressor, Cterminal allalpha;
multimeric complexes	3zql_AB 3zql_CD
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3zql_B interface=34,35,45,46,47,49,50, vsiwmhpeptlsrdqivraavkvadtegveaasMRrvaaelgagTMSlYYyvptkedlvelmvdevigetrlpdrpgpdwraaltlaanekralwlrhpwlatawrnghpvwgpnslrqqefvlgtlgvfdlqvdellsliglyngyvesfvrnevgwleearrtkvdmrewmrrsgpyaqqlvdsgeypmfarvlaetvaphmgpdqrfrsglerlldsigasld
interface signature	MRTMSYY

Estimated binding specificities ?

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# IC=7.965 IC/col=0.996 n_of_columns=8

specificity:

A |   0   0   0  96   0  11  67  67
C |  96   0   0   0  96   9   9   9
G |   0  96   0   0   0  67   9  11
T |   0   0  96   0   0   9  11   9

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Dendrogram of similar interfaces ?

matrix format

  
  MTRG--TTMGSCYTYT   L      +--------------3zql_B    
                         +--3 
  MTRGTGPT--ATYTWT   L   !  !         +----5yej_B    
                         !  +---------2 
  VT--AGDT--TTYTLA   L --4            !    +5gpc_B    
                         !            +----1 
  ----TTRG----YTWA   L   !                 +7jnp_A    
                         ! 
  ----TGKG----YCFA   L   +-----------------4pxi_B

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updated Tue Dec 19 08:34:10 2023