interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF FOXO1 DBD BOUND TO IRE DNA
(Forkhead box protein O1)
referenceMarmorstein et al. Structure 16 1407 2008
sourceHomo sapiens
experimentX-ray (resolution=2.20, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
multimeric complexes4lg0_AB 5dui_AB 6lbi_CD 6lbi_GH 6lbi_KL
reference complex3co6_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHSL

Estimated binding specificities ?

readout + contactlogo
# IC=4.123 IC/col=0.825 n_of_columns=5 specificity:   
A |  10  10   0   0   0
C |  12  10  10   0   0
G |  10  66  12   0   0
T |  64  10  74  96  96
scan!

home
updated Mon Dec 18 07:45:35 2023