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structure name4 CRYSTAL STRUCTURES OF CAP-DNA WITH ALL BASE-PAIR SUBSTITUTIONS AT POSITION 6, CAP-[6A;17T]ICAP38 DNA
(Catabolite gene activator)
referenceBerman et al. J.Mol.Biol. 357 173 2006
sourceEscherichia coli
experimentX-ray (resolution=2.80, R-factor=0.280)
structural superfamilycAMP-binding domain-like;"Winged helix" DNA-binding domain;
sequence familyCyclic nucleotidebinding domain; Bacterial regulatory proteins, crp famil;
multimeric complexes1cgp_AB 1lb2_ABE 3iyd_ACDFGH 3n4m_ABC 5ciz_AB 6pb4_CDFGH 6pb5_CFGH 6pb6_CDFGH
reference complex3n4m_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSRER

Estimated binding specificities ?

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# IC=2.260 IC/col=0.452 n_of_columns=5 specificity:   
A |   3  10  42   9  67
C |   3  10  18  11   9
G |   3  63  18  67  11
T |  87  13  18   9   9
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updated Mon Dec 18 06:31:27 2023