interface graph thumbnail
legend  pdf

structure name4 CRYSTAL STRUCTURES OF CAP-DNA WITH ALL BASE-PAIR SUBSTITUTIONS AT POSITION 6, CAP-ICAP38 DNA
(Catabolite gene activator)
referenceBerman et al. J.Mol.Biol. 357 173 2006
sourceEscherichia coli
experimentX-ray (resolution=2.80, R-factor=0.287)
structural superfamilycAMP-binding domain-like;"Winged helix" DNA-binding domain;
sequence familyCyclic nucleotidebinding domain; Bacterial regulatory proteins, crp famil;
multimeric complexes1cgp_AB 1lb2_ABE 3iyd_ACDFGH 3n4m_ABC 5ciz_AB 6pb4_CDFGH 6pb5_CFGH 6pb6_CDFGH
reference complex3n4m_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQSRETR

Estimated binding specificities ?

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# IC=2.402 IC/col=0.480 n_of_columns=5 specificity:   
A |  16   9   8   3  67
C |  16   9   8   3   9
G |  19  69  10  85   9
T |  45   9  70   5  11
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updated Mon Dec 18 06:31:20 2023