| structure name | HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE POISON TOPOTECAN AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX (DNA topoisomerase I) |
| reference | Burgin Jr. et al. Proc.Natl.Acad.Sci.USA 99 15387 2002 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.10, R-factor=?) |
| structural superfamily | Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment;DNA breaking-rejoining enzymes;Eukaryotic DNA topoisomerase I, dispensable insert domain; |
| sequence family | Eukaryotic DNA topoisomerase I, DNA bind; Eukaryotic DNA topoisomerase I, catalyti; |
| redundant complexes | 1r49 1tl8 1seu 1sc7 1t8i 1a31 1a35 1a36 1rrj 1rr8 1lpq 1ej9 |
| reference complex | 1a31_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Dendrogram of similar interfaces ?
matrix format--ECRA--YAMCKT--NTKT--------NT +------1k4t_A +------------1 NT--RGMGYAMCKT--NCKTDA--TT---- L +--------2 +------2b9s_A ! ! --------------RG------RG------ L --3 +-------------------3m4a_A ! --------------------------NT-- +----------------------------2b9s_B |
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updated Mon Dec 18 05:14:33 2023