interface graph thumbnail
legend  pdf

structure nameTWO HUMAN C-FOS:C-JUN:DNA COMPLEXES
(C-JUN PROTO-ONCOGENE PROTEIN)
referenceGlover et al. Nature 373 257 1995
sourceHOMO SAPIENS
experimentX-ray (resolution=3.05, R-factor=0.230)
structural superfamilyLeucine zipper domain;A DNA-binding domain in eukaryotic transcription factors;
sequence familybZIP transcription factor; Basic region leucine zipper;
multimeric complexes1a02_FJN 1fos_EF 1fos_GH 1jnm_AB 1s9k_CDE 2h7h_AB 5t01_AB
reference complex5t01_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNAASR

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |  13  13  96   0   0
C |  13  16   0  96   0
G |  13  54   0   0   0
T |  57  13   0   0  96
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updated Mon Dec 18 05:06:25 2023