7zkl_H : 3D-footprint complex

structure name	X-RAY STRUCTURE OF THE COMPLEX BETWEEN HUMAN ALPHA THROMBIN AND A PSEUDO-CYCLIC THROMBIN BINDING APTAMER (TBA-NNP/DDP) - CRYSTAL FORM ALPHA
reference	Troisi et al. 'Mol ? ? 2022
experiment	X-ray (resolution=3.18, R-factor=0.193)
structural superfamily	Trypsin-like serine proteases;
sequence family	Trypsin;
multimeric complexes	1hap_HL 1hut_HL 4dih_HL 4dii_HL 4lz4_CD 6evv_HL 6gn7_HL 7zkl_HL
reference complex	6z8v_H
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7zkl_H interface=9,66,67,70,71,73,75,78, ivegsdaeIgmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendllvrigkHSrtRYeRnIekIsmlekiyihprynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf
interface signature	IHSRYRII

Estimated binding specificities ?

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# IC=9.038 IC/col=0.695 n_of_columns=13

specificity:

A |  14   0   0   0  24  24  24  24  24   4   0   0   0
C |  14   0   0   0  24  24  24  24  24   4   0   0   0
G |  52   0   0  96  24  24  24  24  24  84   0   0  96
T |  16  96  96   0  24  24  24  24  24   4  96  96   0

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updated Tue Dec 19 02:02:08 2023