interface graph thumbnail
legend  pdf

structure nameX-RAY STRUCTURE OF THE COMPLEX BETWEEN HUMAN ALPHA THROMBIN AND NU172, A DUPLEX/QUADRUPLEX 26-MER DNA APTAMER, IN THE PRESENCE OF POTASSIUM IONS.
referenceRusso Krauss et al. 'Nucleic 46 12177 2018
sourceHOMO SAPIENS
experimentX-ray (resolution=2.50, R-factor=?)
structural superfamilyTrypsin-like serine proteases;
reference complex4dih_L 6z8v_H
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIHRYRNII/C

Estimated binding specificities ?

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# IC=9.589 IC/col=0.738 n_of_columns=13 specificity:   
A |   2   0   0   0  24   2  24  24  24  16   0   0   4
C |   2   0   0   0  24   2  24  24  24  19   0   0   4
G |  88   0   0  96  24  90  24  24  24  45  96   0  81
T |   4  96  96   0  24   2  24  24  24  16   0  96   7
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updated Sat Dec 16 10:08:47 2023