7f75_F : 3D-footprint complex

Interface of input file ?

structure name	CRYO-EM STRUCTURE OF SPX-DEPENDENT TRANSCRIPTION ACTIVATION COMPLEX (RNA POLYMERASE SIGMA FACTOR SIGA)
source	BACILLUS SUBTILIS
experiment	NMR
structural superfamily	Sigma2 domain of RNA polymerase sigma factors;Sigma3 and sigma4 domains of RNA polymerase sigma factors;
sequence family	Sigma70 region 3; Sigma70 region 2; Sigma70, region 4; Sigma70 factor, region 12; HTH DNA binding domain;
redundant complexes	7ckq
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7f75_F interface=3,4,7,21,42,45,55,57,82,88,89,90,92,93,96,97,100,101,103,115,118,171,179,182,243,245,246,249, dpVRmyLkeigrvnllsakeEiayaqkieegdeeskrrlaeAnlRlvvsiakryVgRgmlfldliqegnmglmkavekfdyRkgykfSTYaTWwiRQaiTRaIadqartiripvHmvEtinklirvqrqllqdlgreptpeeiaedmdltpekvreilkiaqepvsletpIgeeddshLgdFiedqeatspsdhaayellkeqledvldtltdreenvlrlrfglddgrtrtleevgkvfgvTrERirQieakalrklrhpsrskrlkdfle
interface signature	VRLEARVRRSTYTWRQTRIHEILFTERQ

Estimated binding specificities ?

contact

# IC=16.326 IC/col=0.510 n_of_columns=32

specificity:

A |   7  24  24  24   7  24  24  24  24  24  24  24  24  24  24  24  24  24  90   0   0  11   0   0  96   9  88  96   0   9   0   2
C |   7  24  24  24   6  24  24  24  24  24  24  24  24  24  24  24  24  24   2   0   0  64   0   0   0   4   4   0   0   9   0   2
G |   9  24  24  24  76  24  24  24  24  24  24  24  24  24  24  24  24  24   2   0  96   9   0   0   0   7   2   0   0  66  96  88
T |  73  24  24  24   7  24  24  24  24  24  24  24  24  24  24  24  24  24   2  96   0  12  96  96   0  76   2   0  96  12   0   4

scan!

Dendrogram of similar interfaces ?

matrix format

  
  VGRGLG----ETAT--RT--------VART------------RA------STTAYATAWA--RAQTTARGIA------HTEA------------IG--------LGFG--TT--ECRT--QT   L                    +----7f75_F    
                                                                                                                                                    ! 
  TAQALAITLTET--NTRTLT----------LA------FADA--RA--RTSCTAYATCWTWC--QCEARG------ITHGKC------------------------------RGET--RC--   L   +----------------3     +6omf_F    
                                                                                                                                   !                !   +-1 
  --------------NTRGLT----YA----FG------FAEA--RAFAKTSTTAYATCWTWTRCQTNARG----RTVGHTECIT----RARAATIGDGEG--SG--FGLTTTRGECRCRTQC   L   !                +---2 +4xln_F    
                                                                                                                                 --5                    ! 
  ------------------LT----------------KTFAEA--RAFA--SATAYATA--WTRA------------------------------IG----DG----FG--------------       !                    +6kqf_F    
                                                                                                                                   ! 
  --------------NTRTLT------------------FADA--------STTCYATTWTWG--QA--RG------------------------------------------RCEC----QT       !       +-------------6wmr_Z    
                                                                                                                                   +-------4 
  --------------NTRGLTIGKTYT------LTKT----EA----YAKTSATAYATAWGWTRCQATTRGITATRTVAHGET--NANA--RA------------------------------               +-------------6n4c_F

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updated Mon Dec 18 20:10:52 2023