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structure nameCRYSTAL STRUCTURE OF HUMAN KLF4 ZINC FINGER DNA BINDING DOMAIN IN COMPLEX WITH NANOG DNA
(Krueppel-like factor 4)
referenceFerreon et al. 'Nat 12 5579 2021
sourceHomo sapiens
experimentX-ray (resolution=2.14, R-factor=0.218)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex2wbs_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSHRDERRDH

Estimated binding specificities ?

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# IC=8.358 IC/col=1.045 n_of_columns=8 specificity:   
A |  13   0   0   0   0   0  13   0
C |  15   0   0   0   0   0  13   0
G |  41  96  96  96   0  96  13  96
T |  27   0   0   0  96   0  57   0
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updated Mon Dec 18 18:38:51 2023